The 65th Infantry Regiment, nicknamed "The Borinqueneers" from the original Taíno name of the island (Borinquen), is a Puerto Rican regiment of the United States Army. The regiment's motto is Honor et Fidelitas, Latin for Honor and Fidelity. The Army Appropriation Bill created by an act of Congress on 2 March 1898, authorized the creation of the first body of native troops in Puerto Rico. On 30 June 1901, the "Porto Rico Provisional Regiment of Infantry" was organized. On July 1, 1908, Congress incorporated the regiment into the Regular Army as the Puerto Rico Regiment of Infantry, United States Army. On May 14, 1917, the Regiment was activated and additional men were assigned, with the unit being sent to serve at Panama. On June 4, 1920, the Regiment was renamed 65th Infantry. During World War II, the Regiment saw action throughout Europe, especially France and Germany, participating in Naples-Foggia, Rome-Arno and Rhin. Several Purple Hearts were handed posthumously to members of the 65th Regiment, and the Medal of Honor was granted to Capt. Eurípides Rubio, Héctor Santiago, Carlos Lozada and Fernando García.

The 65th Infantry Regiment participated in World War I, World War II, the Korean War, and in what is known in the United States as the War on Terror. On April 13, 2016, the 65th Infantry was awarded the Congressional Gold Medal.